Why do people continue their addiction even when they know it is harming them and can cause death? Addiction is a disorder affecting a wide range of people. Drugs are not the only things people are addicted to. Other addictions are alcohol, food, sex, exercising and many more. Long-term abusers have many behavioral consequences, because their brain functioning changes. These changes can control the use of drugs despite the consequences. Over time people use more and more of the substance since they gain a tolerance and need to get a better “high”. Their reward system controls the body and what motivates the person to repeat behaviors, which can lead a person to take a drug again or again. Addiction often involves cycles of relapse and remission just like other chronic diseases. Without treatment or arrangement in recovery activities, addiction is progressive and can result in disability or premature death.